Status:
COMPLETED
Duration of Hypothermia for Neuroprotection After Pediatric Cardiac Arrest
Lead Sponsor:
University of Pittsburgh
Collaborating Sponsors:
National Institute of Neurological Disorders and Stroke (NINDS)
Laerdal Medical
Conditions:
Cardiac Arrest
Brain Injury
Eligibility:
All Genders
1-17 years
Phase:
PHASE2
Brief Summary
In this study, children who survive cardiac arrest will be evaluated whether 24 or 72 hours of whole body hypothermia (cooling) during recovery is better to help prevent brain injury and improve outco...
Detailed Description
Cooling has been shown to decrease the amount of brain injury that can occur after heart attacks in adults and in newborn babies with birth asphyxia (a lack of blood flow and oxygen to the fetus). It ...
Eligibility Criteria
Inclusion
- Chest compressions by a health care worker Age 1 wk - 17 yr ROSC attained PICU attending decides to cool Central venous or arterial catheter Glasgow Coma Score ≤ 8
Exclusion
- Other acute brain injury (TBI, meningitis) Do not resuscitate status Pregnancy Absolute contraindication to MRI Brain death evaluation Metabolic disorder Active hemorrhage Pre-existing coagulation defect
Key Trial Info
Start Date :
October 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2015
Estimated Enrollment :
34 Patients enrolled
Trial Details
Trial ID
NCT00797680
Start Date
October 1 2008
End Date
April 1 2015
Last Update
January 18 2016
Active Locations (1)
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1
Children's Hospital of Pittsburgh
Pittsburgh, Pennsylvania, United States, 15213