Status:
COMPLETED
Dental Study in Cancer Patients With Central Venous Catheters
Lead Sponsor:
Rajesh Lalla
Conditions:
Cancer
Eligibility:
All Genders
18+ years
Brief Summary
Patients who are preparing to receive chemotherapy are asked to have their teeth cleaned before starting treatment as standard of care. This research study is being done to see if having dental cleani...
Eligibility Criteria
Inclusion
- Inclusion criteria
- Patients willing and able to provide written informed consent for the study.
- Patients diagnosed with cancer and being treated at the University of Connecticut Health Center.
- Patients scheduled to receive or who have received a central venous catheter
- Patients who have at least one tooth.
- Exclusion criteria
- Patients under the age of 18
- Patients who have received any antibacterial in the time period starting 48 hours before the dental cleaning. This includes systemic antibacterials and topical antibacterials in the oral cavity or at/through the CVC site. (Topical antibacterials at other sites are allowed; antifungal and antiviral agents in any form are allowed).
- Patients who plan to use antibacterials within the 24 hours after the procedure (until the final blood sample is obtained).
- Patients with a documented blood stream infection within 1 month prior to proposed dental cleaning.
- Patients with a clinically significant coagulation disorder or patients on warfarin.
- Patients who require antibiotic prophylaxis as per American College of Cardiology/American Heart Association (ACC/AHA) 2007 guidelines, namely;
- patients who have had a cardiac transplantation,
- incomplete cardiac valve repair,
- complete cardiac valve repair in last 6 months,
- prior history of infective endocarditis ,
- patients with a prosthetic cardiac valve.
- Patients with any other condition which might preclude participation in the opinion of the patient's physician(s) or the study PI's.
Exclusion
Key Trial Info
Start Date :
September 1 2012
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2012
Estimated Enrollment :
27 Patients enrolled
Trial Details
Trial ID
NCT00798330
Start Date
September 1 2012
End Date
December 1 2012
Last Update
August 27 2020
Active Locations (1)
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1
University of Connecticut Health Center
Farmington, Connecticut, United States, 06030