Status:
COMPLETED
How Similar Are Changes to the Surface of the Eye When Two Different Glaucoma Eye Drops Are Used?
Lead Sponsor:
Wills Eye
Collaborating Sponsors:
Pfizer
Conditions:
Glaucoma
Eligibility:
All Genders
21+ years
Phase:
PHASE4
Brief Summary
To determine whether one glaucoma eye drop is less likely to cause changes to the surface of the eye (conjunctiva) than another. The two different prostaglandins are Xalatan and Travatan Z.
Detailed Description
Two groups will be entered into this study: group 1 will be naive to treatment and group 2 will be using Xalatan for at least one month before enrollment. Both groups will be using one drop at bedtime...
Eligibility Criteria
Inclusion
- Age 21 or older
- Able to understand protocol and agree to 3 visits
- Any type of glaucoma
- Selective laser trabeculoplasty, Argon laser trabeculoplasty, peripheral iridotomy accepted
- Naïve: No prior glaucoma treatment (medical or surgical)
- If patient non-compliant, must be off meds 3 months
- Xalatan: At least one month use
Exclusion
- Both Groups: Any history of ocular surface disease
- Dry eye syndrome or prior Restasis use
- Prior ocular surgery other than cataract extractions
- Uveitis or other inflammatory disease of the eye or adnexa
- Systemic medications that might influence ocular inflammation
- Any active inflammation or infection
- Pregnancy or intention to become pregnant
- Naïve: Prior use of topical glaucoma medication unless off for 3 months.
- Use of preserved artificial tear preparations in last 30 days and more than one year history of chronic use
- Xalatan: Prior use of Travatan or Travatan Z
Key Trial Info
Start Date :
November 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2011
Estimated Enrollment :
58 Patients enrolled
Trial Details
Trial ID
NCT00798694
Start Date
November 1 2008
End Date
February 1 2011
Last Update
July 12 2018
Active Locations (1)
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1
Wills Eye Glaucoma Service
Philadelphia, Pennsylvania, United States, 19107