Status:

COMPLETED

Efficacy and Safety Study of Ataciguat Versus Placebo in Patients With Neuropathic Pain

Lead Sponsor:

Sanofi

Conditions:

Pain

Eligibility:

All Genders

18-75 years

Phase:

PHASE2

Brief Summary

The primary objective of this study is to assess the efficacy of ataciguat versus placebo in reducing pain intensity in patients with neuropathic pain. The secondary objective is to assess the safety...

Detailed Description

This study consists of two consecutive 28 day treatment periods which are separated by a 2 week medication free period and a safety follow-up period of 2 weeks after the second treatment period.

Eligibility Criteria

Inclusion

  • Patients with chronic neuropathic pain due to diabetic polyneuropathy or a nerve lesion following surgery. The pain must be present for more than 3 months.

Exclusion

  • Presence or history of cancer within the past five years
  • Patients with a history of HIV infection
  • Patients with active hepatitis B or C
  • Patients with any pain other than the neuropathic pain of greater or equal severity
  • Patients with a diabetes mellitus for less than 6 months
  • The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.

Key Trial Info

Start Date :

November 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

September 1 2009

Estimated Enrollment :

62 Patients enrolled

Trial Details

Trial ID

NCT00799656

Start Date

November 1 2008

End Date

September 1 2009

Last Update

April 1 2011

Active Locations (3)

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Page 1 of 1 (3 locations)

1

Sanofi-Aventis Administrative Office

Vienna, Austria

2

Sanofi-Aventis Administrative Office

Prague, Czechia

3

Sanofi-Aventis Administrative Office

Bucharest, Romania