Status:
COMPLETED
Effects of an Herbal Topical Cream on Osteoarthritis Symptoms, Biomarkers, and Disease Progression in the Knee
Lead Sponsor:
Stanford University
Conditions:
Osteoarthritis
Eligibility:
All Genders
40-70 years
Phase:
EARLY_PHASE1
Brief Summary
Arthritis Relief Plus (ARP) Cream is a natural, herbal cream that has been shown to provide pain relief and decreased stiffness. Anecdotal reports suggest that pain may continue to be reduced months a...
Detailed Description
General Procedure: Subjects will be screened for: a history of knee pain and surgery by questionnaire; kidney disease as determined by blood creatinine levels; knee diameter less than 17cm and body di...
Eligibility Criteria
Inclusion
- Men and women between 40-70 years old
- Have a history of knee pain
- Exhibit mild osteoarthritis on the knee, as determined by Dr. Gold through MRIs and radiographs (if available).
Exclusion
- Outside of age range
- Prior knee surgery
- History of knee or knee ligament instability
- History of intermittent or persistent knee joint swelling
- History of trauma to the knee or lower extremities resulting in fracture, tears of menisci, ligaments or joint capsule, or cartilage damage
- Unable to have MRI scan due to the presence of metallic internal devices that would represent a risk factor for MRI and known or suspected pregnancy.
- History of corticosteroid use
- Kidney Disease
- Knee diameter greater than 17cm and body diameter greater than 60 cm due to the physical constraints of the MRI
Key Trial Info
Start Date :
December 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2010
Estimated Enrollment :
22 Patients enrolled
Trial Details
Trial ID
NCT00800098
Start Date
December 1 2008
End Date
February 1 2010
Last Update
September 25 2019
Active Locations (1)
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1
Stanford University School of Medicine
Stanford, California, United States, 94305