Status:

COMPLETED

Intensive Combined Chelation Therapy for Iron-Induced Cardiac Disease in Patients With Thalassemia Major

Lead Sponsor:

Ospedale Microcitemico

Collaborating Sponsors:

Azienda Sanitaria Locale di Cagliari

Conditions:

Iron Overload

Cardiomyopathy

Eligibility:

All Genders

18+ years

Phase:

PHASE4

Brief Summary

Myocardial iron overload is the leading cause of death in patients with beta-thalassemia major (TM). Therapy with deferoxamine (DFO) combined with deferiprone (DFP) reduces myocardial iron and improve...

Eligibility Criteria

Inclusion

  • Cardiomyopathy secondary to iron overload

Exclusion

  • Heart failure

Key Trial Info

Start Date :

December 1 2001

Trial Type :

INTERVENTIONAL

End Date :

June 1 2006

Estimated Enrollment :

Patients enrolled

Trial Details

Trial ID

NCT00800761

Start Date

December 1 2001

End Date

June 1 2006

Last Update

December 2 2008

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Adult Talassemic Center, Ospedale Microcitemico

Cagliari, Sardinia, Italy, 09121