Status:

COMPLETED

Intravenous Remifentanil Patient-controlled Analgesia (PCA) and Epidural Patient Controlled Epidural Analgesia (PCEA) for Labor Analgesia

Lead Sponsor:

Hadassah Medical Organization

Conditions:

Labor

Pain

Eligibility:

FEMALE

18-40 years

Phase:

PHASE4

Brief Summary

Women requesting analgesia do not always wish to receive a potent analgesic method, and may fear the risks of epidural analgesia. Study Aim: To determine whether remifentanil is effective for labor a...

Eligibility Criteria

Inclusion

  • Inclusion criteria:
  • Healthy women
  • American Society of Anesthesiologists physical status class I or II
  • Body weight less than 110 kg
  • In active labor (including induced labor and premature rupture of membranes)
  • Cervical dilatation at 2-6 cm
  • Regular contractions
  • Age between 18 and 40 years old
  • Gestational age greater than 36 completed weeks
  • Singleton pregnancy and vertex presentation
  • Exclusion criteria:
  • Contraindication for epidural analgesia (bleeding diathesis, neuropathy, severe scoliosis, previous spine surgery, local anesthetic allergy)
  • Narcotic administration in the previous 2 hours
  • Previous uterine surgery
  • Pre-eclampsia and the inability to adequately understand the consent form
  • Blocked nose, and any indication patient for whom epidural analgesia is medically indicated (cardiac disease, suspected difficult airway)

Exclusion

    Key Trial Info

    Start Date :

    February 1 2010

    Trial Type :

    INTERVENTIONAL

    Allocation :

    ACTUAL

    End Date :

    July 1 2012

    Estimated Enrollment :

    50 Patients enrolled

    Trial Details

    Trial ID

    NCT00801047

    Start Date

    February 1 2010

    End Date

    July 1 2012

    Last Update

    April 21 2015

    Active Locations (1)

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    Hadassah Medical Organization

    Jerusalem, Israel