Status:
TERMINATED
The Effect of Dexamethasone on the Duration of Interscalene Nerve Blocks With Ropivacaine or Bupivacaine
Lead Sponsor:
The Cleveland Clinic
Conditions:
Anesthesia, Local
Shoulder Surgery
Eligibility:
All Genders
18-75 years
Phase:
NA
Brief Summary
This study will test the hypothesis that adding dexamethasone significantly prolongs the duration of ropivacaine and bupivacaine analgesia, and that the magnitude of the effect differs among the two l...
Detailed Description
This is a double-blinded randomized study of four groups of patients undergoing shoulder surgery using interscalene nerve blocks. Participants will be randomized into one of four groups: * Ropivacain...
Eligibility Criteria
Inclusion
- Age between 18 and 75 years
- Patients undergoing shoulder procedures, such as rotator cuff repair, capsular shift, shoulder arthroplasty, subacromial decompression
Exclusion
- Contraindications to interscalene block (Coagulopathy, infection at the needle insertion site, moderate to severe chronic obstructive pulmonary disease, contralateral pneumothorax or diaphragmatic paralysis)
- Pregnancy
- Pre-existing neuropathy involving the surgical limb
- Systemic glucocorticoid treatment (for 2 weeks or more) within six months of surgery
- Chronic opioid use (greater than 30 mg oral oxycodone equivalent per day)
Key Trial Info
Start Date :
November 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2010
Estimated Enrollment :
218 Patients enrolled
Trial Details
Trial ID
NCT00801138
Start Date
November 1 2008
End Date
November 1 2010
Last Update
May 1 2017
Active Locations (1)
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1
Cleveland Clinic
Cleveland, Ohio, United States, 44195