Status:
COMPLETED
Characterization of Early Markers of Choroidal Neovascularization
Lead Sponsor:
Association for Innovation and Biomedical Research on Light and Image
Conditions:
Age-related Macular Degeneration
Eligibility:
All Genders
50+ years
Brief Summary
To this study and identify the sequence of alterations occurring in the chorioretinal interface during progression of AMD from "dry" AMD to sight-threatening chorioretinal neovascularization (CNV).
Detailed Description
The primary statistical objective of this study is to identify the sequence of alterations occurring in the chorioretinal interface during progression of AMD from risk "dry" AMD to sight-threatening c...
Eligibility Criteria
Inclusion
- Written informed consent
- Age over 50 years
- Any race and any sex
- Clinical diagnosis of exudative AM;D in one eye (non-stud eye) and the presence of the following characteristics in the second eye (study eye, eye to be treated):
- At least 5 or more intermediate (\> 63 µm) or larger soft drusen AND/OR Confluent drusen within 3000 µm of the fovea center
- Hyperpigmentation
Exclusion
- History of medical condition that would preclude scheduled study visits
- History of ophthalmic disease in the study eye other than AMD
- Clinical signs of myopic retinopathy, or refraction higher than -8 diopter power.
- Intraocular surgery in the study eye within 60 days prior enrollement
- Evidence of past or present CNV in the study eye
Key Trial Info
Start Date :
December 1 2005
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2014
Estimated Enrollment :
60 Patients enrolled
Trial Details
Trial ID
NCT00801541
Start Date
December 1 2005
End Date
June 1 2014
Last Update
March 19 2015
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
AIBILI - Clinical Trial Center
Coimbra, Coimbra District, Portugal, 3000-548