Status:

COMPLETED

A Study for Patients With Type 2 Diabetes Mellitus

Lead Sponsor:

Eli Lilly and Company

Conditions:

Diabetes Mellitus, Type 2

Eligibility:

All Genders

18-70 years

Phase:

PHASE2

Brief Summary

A multicenter, multinational, randomized,double-blind, placebo-controlled study in patients with Type 2 Diabetes Mellitus (T2DM). Patients with inadequate glycemic control using diet and exercise alon...

Eligibility Criteria

Inclusion

  • Have type 2 diabetes mellitus for at least 6 months prior to entering the trial.
  • Treated with diet and exercise alone or in combination with at least 1000 milligrams (mg)/day of metformin for at least 2 months prior to screening.
  • Have a glycosylated fraction of hemoglobin A (HbA1c) value of 7.0% - 10.0% at screening
  • Women of child-bearing potential must test negative for pregnancy at screening and agree to abstain from heterosexual intercourse for the duration of the study, or use 2 effective forms of birth control during the study.
  • Have a body mass index (BMI) between 25 and 40 kilograms per square meters kg/m\^2) at screening
  • Stable weight during the 3 months prior to screening.

Exclusion

  • Use any antidiabetic agent other than metformin during the 2 months prior to screening.
  • Have a gastrointestinal disease that significantly impacts gastric emptying or motility or have undergone bariatric surgery.
  • Are currently taking prescription or over-the counter medications to promote weight loss.
  • Have been previously diagnosed with pancreatitis
  • Women who are breastfeeding.
  • Have a history of myocardial infarction, unstable angina, coronary artery bypass graft (CABG), percutaneous coronary intervention, transient ischemic attack, stroke or decompensated congestive heart failure in the past 6 months.
  • Have poorly controlled hypertension

Key Trial Info

Start Date :

December 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

January 1 2010

Estimated Enrollment :

247 Patients enrolled

Trial Details

Trial ID

NCT00804986

Start Date

December 1 2008

End Date

January 1 2010

Last Update

July 14 2011

Active Locations (60)

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Page 1 of 15 (60 locations)

1

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

Bermuda Dunes, California, United States, 92203

2

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

Chula Vista, California, United States, 91911

3

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

Huntington Beach, California, United States, 92648

4

For additional information regarding investigative sites for this trial, contact 1-877-CTLILLY (1-877-285-4559, 1-317-615-4559) Mon - Fri from 9 AM to 5 PM Eastern Time (UTC/GMT - 5 hours, EST), or speak with your personal physician.

Long Beach, California, United States, 90806