Status:

TERMINATED

Clinical Trial of Postmastectomy Radiotherapy in Breast Cancer With One to Three Positive Nodes

Lead Sponsor:

Chinese Academy of Medical Sciences

Conditions:

Breast Cancer

Eligibility:

FEMALE

18-75 years

Phase:

PHASE3

Brief Summary

The purpose of this study is to evaluate postmastectomy radiotherapy in breast cancer patients with one to three positive nodes.

Detailed Description

Eligible breast cancer patients with mastectomy and axillary dissection are randomized into 2 groups:radiotherapy of 50 Gy in 25 fractions within 5 weeks to ipsilateral chest wall and supraclavicular ...

Eligibility Criteria

Inclusion

  • Ipsilateral histologically confirmed invasive breast cancer
  • Undergone total mastectomy and axillary dissection
  • T1-2 and one to three axillary lymph nodes positive
  • A minimum of 10 axillary nodes dissected
  • Fit for chemotherapy(if indicated),endocrine therapy(if indicated)and postoperative irradiation
  • Written,informed consent

Exclusion

  • Patients who undergone previous irradiation to the ipsilateral chest wall and supraclavicular region
  • Previous or concurrent malignant other than non-melanomatous skin cancer
  • Unable or unwilling to give informed consent

Key Trial Info

Start Date :

June 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2012

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT00805597

Start Date

June 1 2008

End Date

February 1 2012

Last Update

August 8 2016

Active Locations (1)

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Cancer Hospital, Chinese Academy of Medical Sciences

Beijing, China, 100021