Status:
COMPLETED
Bilateral Versus Monolateral Repetitive Transcranial Stimulation in Depression
Lead Sponsor:
Institute of Neuroscience, Florence, Italy
Conditions:
Major Depression
Eligibility:
All Genders
18-65 years
Phase:
PHASE4
Brief Summary
Repetitive transcranial magnetic stimulation (rTMS) has been recently FDA approved for the treatment of resistant depression. No accordance exists on which are the involved mechanisms of action and on...
Detailed Description
To compare these different procedures we study patients with unipolar recurrent resistant major depressive disorder in a double-blind, controlled trial randomized to either sequential bilaterally on t...
Eligibility Criteria
Inclusion
- Diagnostic and Statistical Manual-IV criteria for Depressive Major Episode Hamilton Rating Scale for Depression -28 (Ham-D)score ≥ 18
- Failure to respond to a minimum of two courses of antidepressant medications for at least 6 weeks
Exclusion
- Any comorbid axis I disorder (except simple and social phobia)
- Any other significant medical, particularly neurologic, illnesses (seizures, head trauma and brain lesions)
Key Trial Info
Start Date :
September 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
January 1 2009
Estimated Enrollment :
16 Patients enrolled
Trial Details
Trial ID
NCT00806143
Start Date
September 1 2008
End Date
January 1 2009
Last Update
February 24 2011
Active Locations (1)
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1
Institute of Neuroscience
Florence, Italy, 50122