Status:
COMPLETED
A Study of Avastin (Bevacizumab) in Patients With Non-Squamous Non-Small Cell Lung Cancer (NSCLC)
Lead Sponsor:
Hoffmann-La Roche
Conditions:
Non-Squamous Non-Small Cell Lung Cancer
Eligibility:
All Genders
18+ years
Phase:
PHASE3
Brief Summary
This 3 arm study will evaluate the efficacy and safety of adding Avastin versus placebo to a standard chemotherapeutic regimen in patients with advanced or recurrent non-squamous non-small cell lung c...
Eligibility Criteria
Inclusion
- adult patients, \>=18 years of age;
- documented inoperable, locally advanced, metastatic or recurrent non-squamous NSCLC;
- adequate liver and kidney function;
- women of childbearing potential must have a negative serum pregnancy test within 7 days of starting study treatment.
Exclusion
- prior chemotherapy or treatment with another systemic cancer therapy;
- surgery (including open biopsy), significant traumatic injury, or radiotherapy within the last 4 weeks prior to first dose of study treatment;
- brain metastasis or spinal cord compression;
- fertile men, and women of childbearing potential, not using adequate contraception;
- treatment with any other investigational agent, or participation in another clinical trial, within 30 days prior to entering the study.
Key Trial Info
Start Date :
February 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2011
Estimated Enrollment :
1044 Patients enrolled
Trial Details
Trial ID
NCT00806923
Start Date
February 1 2005
End Date
February 1 2011
Last Update
November 2 2016
Active Locations (154)
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1
Bahía Blanca, Argentina, 8000
2
Buenos Aires, Argentina, C1270AAE
3
Buenos Aires, Argentina, C1426ANZ
4
Mendoza, Argentina, 5500