Status:
COMPLETED
Autologous Hematopoietic Stem Cell Transplantation for Early Onset Type 1 Diabetes
Lead Sponsor:
Shanghai Jiao Tong University School of Medicine
Conditions:
Type 1 Diabetes Mellitus
Eligibility:
All Genders
14-35 years
Phase:
PHASE2
Brief Summary
This is a phase II trial in individuals who have been diagnosed with type 1 diabetes within the previous 6 months. The study is evaluating whether stem cell transplantation is safe when chemotherapy a...
Detailed Description
Type 1 diabetes is an autoimmune disease in which the immune system mistakenly attacks the insulin-producing beta cells in the pancreas. Generally, at the time someone is diagnosed with type 1 diabete...
Eligibility Criteria
Inclusion
- Type 1 diabetes mellitus diagnosed by clinical/metabolic parameters and positive anti-GAD antibody
- Less than 6 months from diagnosis
Exclusion
- Previous diabetic ketoacidosis
- Pregnancy
- Severe psychiatric disorder
- Severe organic impairment (renal, hepatic, cardiac, pulmonary)
- Active infectious disease
- Previous or present neoplastic disease
Key Trial Info
Start Date :
February 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2016
Estimated Enrollment :
40 Patients enrolled
Trial Details
Trial ID
NCT00807651
Start Date
February 1 2008
End Date
December 1 2016
Last Update
November 18 2021
Active Locations (1)
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1
Shanghai Jiao Tong University School of Medicine
Shanghai, Shanghai Municipality, China, 200025