Status:
COMPLETED
Does Sildenafil Increase Exercise Performance in Air Pollution?
Lead Sponsor:
Marywood University
Conditions:
Pulmonary Hypertension
Pulmonary Artery Pressure
Eligibility:
MALE
18-30 years
Phase:
NA
Brief Summary
The purpose of this study is to examine if the ingestion of a standard dose of sildenafil enhances the athletic performance of competitive athletes when exercising in a high pollutant environment vers...
Detailed Description
This study will evaluate effects of sildenafil on exercise performance while breathing high levels of emission exhaust ultrafine and fine particulate matter. Exercise performance will be measured by w...
Eligibility Criteria
Inclusion
- non-asthmatic
- asthmatic
- active participants in endurance sports.
Exclusion
- history of high blood pressure
- history of heart disease
- pulmonary arterial hypertension
- pulmonary emboli
- diagnosis of moderate to severe asthma (FEV1 \<75% predicted)
- pregnant or lactating
Key Trial Info
Start Date :
December 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ESTIMATED
End Date :
February 1 2010
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT00808912
Start Date
December 1 2008
End Date
February 1 2010
Last Update
June 23 2010
Active Locations (1)
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1
Marywood University
Scranton, Pennsylvania, United States, 18509