Status:
UNKNOWN
Mesenchymal Stem Cell for Osteonecrosis of the Femoral Head
Lead Sponsor:
Jianming Tan
Conditions:
Osteochondritis of the Femoral Head
Eligibility:
All Genders
12-60 years
Phase:
EARLY_PHASE1
Brief Summary
Mesenchymal Stem Cells (MSCs) have been shown to have immunosuppressive and repairing properties. Bone marrow mononuclear cells (BMMNCs) have revascularization properties and complimentary effects to ...
Detailed Description
Mesenchymal Stem Cells (MSCs) have been shown to have immunosuppressive and repairing properties. Bone marrow mononuclear cells (BMMNCs) have revascularization properties and complimentary effects to ...
Eligibility Criteria
Inclusion
- Ages: 12 to 60 years old.
- Association Research Circulation Osseous(ARCO) Classification criteria for osteonecrosis of the femoral head: ARCO phase I and phase II.
- Able to give informed consent.
Exclusion
- Pregnant women.
- Previous history of malignancy
- Active infection including hepatitis B, hepatitis C, HIV, or TB as determined by a positive skin test or clinical presentation, or under treatment for suspected TB.
- Evidence of cardiovascular disease, existing congestive cardiac failure on physical exam and/or acute coronary syndrome in the past 6 months.
- Psychiatric illness or mental deficiency making compliance with treatment or informed consent impossible.
- Any illness that in the opinion of the investigator would jeopardize the ability of the Patient to tolerate this treatment.
Key Trial Info
Start Date :
December 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2015
Estimated Enrollment :
15 Patients enrolled
Trial Details
Trial ID
NCT00813267
Start Date
December 1 2009
End Date
August 1 2015
Last Update
October 10 2012
Active Locations (1)
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1
Fuzhou General Hospital
Fuzhou, Fujian, China, 350025