Status:
COMPLETED
Evaluation of a Novel Method for Integrating Insulin Delivery and Glucose Sensing in Adipose Tissue of Diabetic Patients
Lead Sponsor:
Medical University of Graz
Conditions:
Type 1 Diabetes
Eligibility:
All Genders
18-65 years
Phase:
NA
Brief Summary
The study seeks to use microdialysis and microperfusion techniques to assess the feasibility of performing insulin delivery and glucose sensing at a single subcutaneous tissue site.
Detailed Description
Glucose management in type 1 diabetic patients comprises the measurement of glucose in capillary blood obtained by fingersticking and administration of exogenous insulin in the form of a subcutaneous ...
Eligibility Criteria
Inclusion
- Type 1 diabetes mellitus patients aged 18 - 65
- C-peptide negative (≤ 0.05 nmol/L)
- HbA1c (glycosylated haemoglobin A1c) \< 10%
- Body Mass Index: 21 - 30 kg/m2
- Informed consent obtained before any trial-related activities.
Exclusion
- Severe diabetic complications (e.g., proliferative retinopathy, severe nephropathy)
- Female of childbearing potential who is pregnant, breast-feeding or intends to become pregnant or is not using adequate contraceptive methods
- Any condition that would interfere with trial participation or evaluation of results, as judged by the investigator
- Treatment with drugs that could interfere with glucose metabolism and subcutaneous insulin absorption
- Subject with mental incapacity or language barriers
Key Trial Info
Start Date :
February 1 2007
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2007
Estimated Enrollment :
14 Patients enrolled
Trial Details
Trial ID
NCT00813410
Start Date
February 1 2007
End Date
December 1 2007
Last Update
December 23 2008
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Medical University of Graz
Graz, Styria, Austria, A-8036