Status:

COMPLETED

Pharmacosurveillance Data Repository of Patients With and Without History of Anaphylactic Reactions Subsequent to Xolair Dosing

Lead Sponsor:

Genentech, Inc.

Conditions:

Allergic Asthma

Eligibility:

All Genders

Brief Summary

This study will establish a clinical data and serum repository of anaphylaxis cases associated with Xolair administration and control patients who have received Xolair without associated anaphylaxis. ...

Eligibility Criteria

Inclusion

  • Inclusion Criteria for Cases:
  • Confirmed anaphylaxis based on Sampson criteria subsequent to Xolair
  • Inclusion Criteria for Controls:
  • At least 1 patient control among 4 controls who discontinued Xolair for at least 16 weeks but not more than 18 months at enrollment
  • At least one dose of Xolair in the 18 months before the date of the case event (index date)
  • No prior anaphylaxis or other hypersensitivity reaction subsequent to Xolair dosing, including any reactions to its components

Exclusion

    Key Trial Info

    Start Date :

    March 1 2009

    Trial Type :

    OBSERVATIONAL

    Allocation :

    ACTUAL

    End Date :

    January 1 2014

    Estimated Enrollment :

    118 Patients enrolled

    Trial Details

    Trial ID

    NCT00813748

    Start Date

    March 1 2009

    End Date

    January 1 2014

    Last Update

    July 11 2017

    Active Locations (7)

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    Page 1 of 2 (7 locations)

    1

    Investigational Site

    Los Angeles, California, United States, 90025

    2

    Investigational Site

    Valrico, Florida, United States, 33596

    3

    Investigational Site

    Hinsdale, Illinois, United States, 60521

    4

    Investigational Site

    Kansas City, Missouri, United States, 64111