Status:
WITHDRAWN
Automated Ventilator Controlled Weaning vs Daily Spontaneous Breathing Trial in Difficult to Wean ICU Patients
Lead Sponsor:
University of California, San Francisco
Conditions:
Mechanical Ventilation
Weaning
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
This study will compare Drager Smart Care (SC), a commercially available automated ventilator controlled weaning mode to the current daily spontaneous breathing trial (SBT) weaning protocol. The study...
Eligibility Criteria
Inclusion
- Age ≥ 18 years
- Intubated with endotracheal tube
- Requiring mechanical ventilation for \> 72 hours
- Meets weaning criteria: Improvement or resolution of the underlying process that precipitated need for mechanical ventilation, PaO2 ≥ 60 mm Hg on PEEP and FiO2 Requirements of ≤ 8 cm H2O and FiO2 ≤ 0.50, Stable oxygenation: PEEP and FiO2 requirements not increased in the past 24 hrs, Ability to initiate an inspiratory effort and trigger the ventilator, Subject enrollment approved by the primary service attending physician
Exclusion
- Pregnancy
- Patients with tracheostomy or planned tracheostomy prior to attempt to extubate
- Patients with known airway patency issues that are anticipated to delay extubation.
- Patients with neurological injury in whom care is likely to be withdrawn
- Patients with cervical spinal cord injury.
- Prospective subject or surrogate consenter does not fully understand the implications of the study because of a language barrier.
Key Trial Info
Start Date :
November 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2011
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00813839
Start Date
November 1 2008
End Date
October 1 2011
Last Update
May 8 2015
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
San Francisco General Hospital, UCSF Dept. of Anesthesia
San Francisco, California, United States, 94110