Status:

COMPLETED

Airborne Ultrafine and Fine Particulate Matter: A Cause for Endothelial Dysfunction in Man?

Lead Sponsor:

Marywood University

Conditions:

Airway Inflammation

Eligibility:

MALE

18-30 years

Phase:

NA

Brief Summary

The purpose of this study is to examine biological pathways of altered blood vessel function resulting from breathing airborne particulate. Blood artery function in healthy men will be measured after ...

Detailed Description

Hourly ice resurfacing by gas and propane fueled machines creates high levels of ultrafine and fine particulate matter (PM1) in indoor ice rinks. PM1 exposure may disrupt the normal nitric oxide (NO)/...

Eligibility Criteria

Inclusion

  • Healthy male subjects
  • between 18 and 30 years of age
  • participant in endurance sport

Exclusion

  • history of blood clotting
  • history of coagulation problems
  • History of spontaneous pneumothorax

Key Trial Info

Start Date :

May 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

May 1 2009

Estimated Enrollment :

24 Patients enrolled

Trial Details

Trial ID

NCT00814281

Start Date

May 1 2007

End Date

May 1 2009

Last Update

May 21 2009

Active Locations (1)

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Marywood University

Scranton, Pennsylvania, United States, 18509