Status:

UNKNOWN

Mutations in the Epidermal Growth Factor Receptor(EGFR) Gene in Non-Small Cell Lung Carcinoma (NSCLC) and the Relation to Response of Treatment With Erlotinib

Lead Sponsor:

Aarhus University Hospital

Collaborating Sponsors:

University of Aarhus

The Ministry of Science, Technology and Innovation, Denmark

Conditions:

Non-Small Cell Lung Cancer

Eligibility:

All Genders

18+ years

Brief Summary

Recently it has been suggested that specific mutations in the EGFR gene in lung cancer patients is associated with response to a novel drug targeting the EGF system. Recent research also indicates tha...

Detailed Description

Aim: 1. To establish a method for identifying the mutations in the EGFR gene in small clinical samples from lung cancer patients. 2. In a retrospective study(n=500) relate survival to the frequency a...

Eligibility Criteria

Inclusion

  • Patients who are starting treatment with erlotinib and who has who has signed the informed consent.

Exclusion

  • None

Key Trial Info

Start Date :

May 1 2008

Trial Type :

OBSERVATIONAL

Allocation :

ESTIMATED

End Date :

May 1 2011

Estimated Enrollment :

300 Patients enrolled

Trial Details

Trial ID

NCT00815971

Start Date

May 1 2008

End Date

May 1 2011

Last Update

December 31 2008

Active Locations (1)

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1

department of oncology, University Hospital of Aarhus, Nørrebrogade 44

8000 Aarhus, Denmark