Status:

COMPLETED

Transcriptomic Study of ER 4017 Topical Application in Elderly Subject

Lead Sponsor:

L'Oreal

Conditions:

Aging

Eligibility:

MALE

60-75 years

Phase:

NA

Brief Summary

The stratum corneum (SC) is the superficial layer of the epidermis situated at the interface between the body and its outside environment. Its strategic position confers it a crucial role of protectio...

Detailed Description

Structural modifications of the superficial dermis during the aging process associated to alterations in the GAG- and PG profile appear to impact the quality of the dermal epidermal junction (DEJ). Pr...

Eligibility Criteria

Inclusion

  • Phototype I to III
  • Healthy skin on studied skin areas
  • Subject having freely given his informed written consent.
  • Cooperative subject, aware of the necessity to attend all the scheduled appointments during the study.
  • Negative serology for HIV, hepatitis B and hepatitis C
  • No past or present history of allergy linked either to one of the ingredients of the study cosmetic cream tested or to xylocaïne (anesthesia).

Exclusion

  • Cutaneous disease or previous malignant cutaneous lesion on the tested zones.
  • Any treatment able to act on blood coagulation and homeostasis.

Key Trial Info

Start Date :

November 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2008

Estimated Enrollment :

10 Patients enrolled

Trial Details

Trial ID

NCT00818545

Start Date

November 1 2007

End Date

March 1 2008

Last Update

January 7 2009

Active Locations (1)

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Centre de recherche bioclinique -Hopital st louis

Paris, France, 75010