Status:
COMPLETED
Monotherapy Versus Bitherapy in Non-severe Hospitalized Community-acquired Pneumonia
Lead Sponsor:
Swiss National Fund for Scientific Research
Collaborating Sponsors:
University Hospital, Geneva
Conditions:
Community-acquired Pneumonia
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
The purpose of this study is to determine whether a monotherapy with a Beta-Lactam is not inferior to an association of a Beta-Lactam and a macrolide in treating adult patients with community-acquired...
Eligibility Criteria
Inclusion
- Age \>=18 years
- New infiltrate on chest X-ray, unexplained by another disease process
- Presence of at least two of the following findings suggestive of pneumonia: fever or hypothermia, new or increasing cough, sputum production, pleuritic chest pain, tachypnea, dyspnea or focal signs on chest examination
- Need for hospitalization as defined by the emergency physician in charge of the patient
Exclusion
- Allergy to one of the study drugs
- Pregnancy
- Severe immunosuppression
- Recent (\<14 d) hospitalization, or currently hospitalized since \> 48 hours
- Residency in a nursing home
- Previous use of more than 24 hours of any antibiotic
- Severe community-acquired pneumonia
Key Trial Info
Start Date :
January 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
April 1 2013
Estimated Enrollment :
601 Patients enrolled
Trial Details
Trial ID
NCT00818610
Start Date
January 1 2009
End Date
April 1 2013
Last Update
April 25 2013
Active Locations (6)
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1
HFR-Fribourg, Hôpital Cantonal
Fribourg, Canton of Fribourg, Switzerland, 1708
2
Stadtspital Triemli
Zurich, Canton of Zurich, Switzerland, 8063
3
Centre Hospitalier du Centre du Valais
Sion, Valais, Switzerland, 1950
4
Hôpitaux Universitaires de Genève
Geneva, Switzerland, 1211