Status:
COMPLETED
Comparison of the Fixed Combinations of Brimonidine/Timolol and Dorzolamide/Timolol in Subjects With Open-Angle Glaucoma or Ocular Hypertension
Lead Sponsor:
Allergan
Conditions:
Open-Angle Glaucoma
Ocular Hypertension
Eligibility:
All Genders
18+ years
Phase:
PHASE4
Brief Summary
This study compares the efficacy and tolerability/comfort of brimonidine/timolol and dorzolamide/timolol in patients with open-angle glaucoma or ocular hypertension. In an investigator masked randomis...
Eligibility Criteria
Inclusion
- Male or female over 18 years
- Female subjects of childbearing potential must have negative pregnancy test and practice contraception
- Subjects must have confirmed diagnosis of primary open-angle glaucoma or ocular hypertension in both eyes
- Subjects who are or have been insufficiently responsive to IOP reducing monotherapy and use of either study medication is deemed appropriate
- Subjects able to complete questionnaires and provide informed consent
Exclusion
- Female subjects who are pregnant, planning to become pregnant during study period, breast feeding or not practicing a reliable method of birth control
- Subjects wherein the study drugs are contraindicated
- Subjects who have had intraocular surgery with 6 months (3 months for laser)
- Subjects with known side effects/allergy or sensitivity to any component of study treatments
- Subjects with any uncontrolled systemic disease
Key Trial Info
Start Date :
May 1 2005
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2006
Estimated Enrollment :
140 Patients enrolled
Trial Details
Trial ID
NCT00822055
Start Date
May 1 2005
End Date
November 1 2006
Last Update
January 14 2009
Active Locations (1)
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1
Barrie, Ontario, Canada