Status:

COMPLETED

Trial to Evaluate the Ability of a Single Infusion of High-Density Lipoprotein (HDL) to Modulate Markers of Cerebral Ischaemia

Lead Sponsor:

St George's, University of London

Conditions:

Stroke

Eligibility:

All Genders

Phase:

NA

Brief Summary

The plasma concentration of high-density lipoprotein (HDL) can have anti-inflammatory, anti-oxidative and anti-thrombotic effects in addition to being able to remove cholesterol from peripheral tissue...

Detailed Description

Following written informed consent, patients will be randomised to either the placebo or active arm of the study. Bloods will be taken for baseline measurements, and the infusion of either saline (pla...

Eligibility Criteria

Inclusion

  • patients listed for elective carotid endarterectomy

Exclusion

  • pregnant women and women of childbearing age
  • patient with impaired renal function or liver function
  • patients sectioned under the Mental Health Act

Key Trial Info

Start Date :

February 1 2006

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2009

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT00822302

Start Date

February 1 2006

End Date

February 1 2009

Last Update

June 9 2015

Active Locations (1)

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1

St Georges University of London

London, Tooting, United Kingdom, SW17 0QT