Status:

COMPLETED

Trial of Septra for Uncomplicated Skin Abscesses in Patients at Risk for Community Acquired Methicillin-Resistant Staphylococcus Aureus Infection

Lead Sponsor:

59th Medical Wing

Collaborating Sponsors:

U.S. Air Force Office of the Surgeon General

Emergency Medicine Foundation

Conditions:

Abscess

Methicillin-Resistant Staphylococcus Aureus Infection

Eligibility:

All Genders

18-65 years

Phase:

NA

Brief Summary

Patients will be enrolled in a multi-center study (Wilford Hall Medical Center and Brooke Army Medical Center) to prospectively evaluate outcome after treatment for an uncomplicated skin abscess.

Detailed Description

All patients will receive incision and drainage and wound cultures. Patients will then be randomized to 1) septa double strength two pills orally twice a day x 7 days or 2)placebo. Patients will then ...

Eligibility Criteria

Inclusion

  • All patients age 18-65 who present to the emergency department with a skin abscess that requires incision and drainage.

Exclusion

  • Patients with diabetes, HIV, cancer or other immunocompromised patients.
  • Additionally, any patients who received antibiotics within one week of presentation or were hospitalized in previous month will be excluded to minimize potential confounding variables.
  • Pregnant and breastfeeding patients will also be excluded due to possible safety concerns with antibiotic treatment.
  • Patients with abscesses on head, face, perirectal, or periananal regions, abscesses with known tracks or fistulas to deeper structures, or abscesses requiring surgical drainage in an operating room are excluded.
  • Finally, patients with sulfa allergy will be excluded.

Key Trial Info

Start Date :

July 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

June 1 2009

Estimated Enrollment :

139 Patients enrolled

Trial Details

Trial ID

NCT00822692

Start Date

July 1 2008

End Date

June 1 2009

Last Update

December 21 2015

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Wilford Hall Medical Center

Lackland Air Force Base, Texas, United States, 78236

Trial of Septra for Uncomplicated Skin Abscesses in Patients at Risk for Community Acquired Methicillin-Resistant Staphylococcus Aureus Infection | DecenTrialz