Status:

COMPLETED

An Eight-week Study of SSR411298 as Treatment for Major Depressive Disorder in Elderly Patients

Lead Sponsor:

Sanofi

Conditions:

Major Depressive Disorder

Eligibility:

All Genders

60+ years

Phase:

PHASE2

Brief Summary

The primary objective of this study is to evaluate the efficacy of 3 fixed doses of SSR411298 (10, 50 or 200 mg daily) compared to placebo, in elderly patients with Major Depressive Disorder (MDD), ba...

Detailed Description

The study period for a participants is approximately 10 weeks including a screening up to 1 week, 8-week treatment and 1-week follow-up.

Eligibility Criteria

Inclusion

  • Elderly patient with recurrent Major Depressive Disorder

Exclusion

  • Duration of current depressive episode greater than 2 years;
  • Mild depression as measured by standard clinical research scales;
  • Cognitive disturbance;
  • Significant suicide risk;
  • Other psychiatric conditions that would obscure the results of the study;
  • History of failure to respond to antidepressant treatment.
  • The above information is not intended to contain all considerations relevant to a patient's potential participation in a clinical trial.

Key Trial Info

Start Date :

December 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

February 1 2010

Estimated Enrollment :

527 Patients enrolled

Trial Details

Trial ID

NCT00822744

Start Date

December 1 2008

End Date

February 1 2010

Last Update

March 15 2013

Active Locations (7)

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Page 1 of 2 (7 locations)

1

Sanofi-Aventis Administrative Office

Santiago, Chile

2

Sanofi-Aventis Administrative Office

México, Mexico

3

Sanofi-Aventis Administrative Office

Bucharest, Romania

4

Sanofi-Aventis Administrative Office

Moscow, Russia