Status:
COMPLETED
Antagonist/Letrozole in Poor Responders
Lead Sponsor:
Yazd Research & Clinical Center for Infertility
Conditions:
Ovarian Stimulation
Eligibility:
FEMALE
Phase:
PHASE1
PHASE2
Brief Summary
Failure to respond to controlled ovarian hyperstimulation (COH) is still a major concern in assisted reproduction and there is no consensus on the ovarian stimulation choice regime for poor responders...
Detailed Description
All women receive 21 days of an oral contraceptive. A MF protocol will be used for ovarian stimulation in 90 patients. Three days after the last pill, a GnRH-agonist buserelin (Suprefact, Aventis Phar...
Eligibility Criteria
Inclusion
- at least one previous failed IVF cycle in which three or fewer follicles with a mean diameter of 16 mm were achieved, and/or
- serum E2 level measured on the day of hCG administration was ≤500 pg/ml
Exclusion
- day 3 serum FSH level ≥12 mIU/mL
- there is no age limit
Key Trial Info
Start Date :
June 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
October 1 2009
Estimated Enrollment :
120 Patients enrolled
Trial Details
Trial ID
NCT00823004
Start Date
June 1 2008
End Date
October 1 2009
Last Update
December 23 2013
Active Locations (1)
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1
Research and clinical center for infertility
Yazd, Yazd Province, Iran, 8916877391