Status:
RECRUITING
Evaluation of Patients With Non-obstructive Coronary Arteries
Lead Sponsor:
Stanford University
Conditions:
Chest Pain
Ischemia
Eligibility:
All Genders
18+ years
Brief Summary
Patients with angina and non-obstructive CAD are common within clinical practice, but remain a challenge with regard to diagnosis and treatment. When these patients undergo a comprehensive evaluation ...
Detailed Description
This is a prospective registry of patients with chest pain, chest discomfort, breathlessness who do not have a blockage in their heart artery. This condition is known as angina/ischemia and non-obstru...
Eligibility Criteria
Inclusion
- Patient referred for elective coronary angiography because of a reasonable clinical suspicion of coronary ischemia.
- Presence of angina or an anginal equivalent (including chest, back, shoulder, arm, neck, jaw discomfort, or shortness of breath brought on by physical exertion, emotional stress, or certain times of day/month).
Exclusion
- Asymptomatic (such as a pre-op cath)
- Status-post heart transplant
- Age \<18
- Renal insufficiency (creatinine \>1.5)
- Presence of an acute coronary syndrome (STEMI or NSTEMI), Tako-tsubo, an abnormal ejection fraction (EF\<55%), cardiogenic shock, or recent VT/VF
- Presence of another likely explanation of chest pain, such as pulmonary hypertension or aortic stenosis
- History of adverse reaction to any of the medications being used (acetylcholine, nitroglycerin, adenosine, or heparin)
- Currently taking vasoactive medication (such as nitroglycerin)
- Inability to provide an informed consent, including an inability to speak, read, or understand English, Spanish, Chinese, Farsi, Japanese, Korean, Russian, or Vietnamese
- A hearing impairment that won't allow for a typical verbal conversation or a visual impairment that won't allow for reading of the written consent
- Participation in another study (with the exception of the Stanford Gene-PAD study)
- A potentially vulnerable subject (including minors, pregnant women, economically and educationally disadvantaged, decisionally impaired, and homeless people)
Key Trial Info
Start Date :
June 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
June 1 2047
Estimated Enrollment :
2000 Patients enrolled
Trial Details
Trial ID
NCT00823563
Start Date
June 1 2007
End Date
June 1 2047
Last Update
June 5 2025
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Stanford University School of Medicine
Stanford, California, United States, 94305