Status:

UNKNOWN

Unguided Sacroiliac Injection: Effect on Refractory Buttock Pain in Patients With Spondyloarthropathies

Lead Sponsor:

Tabriz University

Conditions:

Spondylarthropathy

Eligibility:

All Genders

16-50 years

Phase:

EARLY_PHASE1

Brief Summary

This study is designed to evaluate the efficacy and safety of guide-free sacroiliac joint (SIJ) injection in refractory sacroiliac pain due to spondyloarthropathies.

Detailed Description

A 20 weeks open-label clinical trial study of 35 patients, with different subtypes of spondyloarthropathies, is conducted In spondyloarthropathy's patients with refractory inflammatory buttock pain (f...

Eligibility Criteria

Inclusion

  • Patients had to fulfill the European Spondylarthropathy Study Group criteria for SpA.
  • The presence of inflammatory buttock pain for at least 4 months (typical night pain and morning stiffness) despite of receiving NSAIDs, corticosteroid and DMARDs (Disease Modifying Anti-Rheumatic Drugs) such as: methotrexate, sulfasalazin and azathioprine.
  • Tenderness over sacroiliac joint: pain over the sacroiliac sulcus with 4-5 kg/cm2 direct pressure.

Exclusion

  • Spinal infections (such as Brucellosis).
  • Local infection in the site of injection.
  • Sacroiliac ankylosis based on pelvic X-Ray (sacroilitis grade IV).
  • Patients who had received anti TNF, corticosteroid pulse or an investigational drugs during 4 months before.

Key Trial Info

Start Date :

September 1 2004

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

February 1 2009

Estimated Enrollment :

35 Patients enrolled

Trial Details

Trial ID

NCT00829543

Start Date

September 1 2004

End Date

February 1 2009

Last Update

February 3 2009

Active Locations (1)

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1

Tabriz Medical University, Rheumatology Department

Tabriz, East Azarbayjan, Iran, +989123355170