Status:
COMPLETED
Memantine Treatment of Compulsive Buying
Lead Sponsor:
University of Minnesota
Conditions:
Compulsive Buying
Eligibility:
All Genders
18-65 years
Phase:
PHASE2
Brief Summary
This is an 8-week, open-labe study of memantine in the treatment of compulsive buying.
Detailed Description
The goal of the proposed study is to evaluate the efficacy of memantine in the treatment of compulsive buying. Sixteen subjects meeting criteria for compulsive buying will receive 8 weeks of open-labe...
Eligibility Criteria
Inclusion
- men and women age 18-65
- current CB using the clinician-administered Structured Clinical Interview for Compulsive buying (SCI-CB)
- buying behavior within 2 weeks prior to enrollment
Exclusion
- infrequent buying (i.e. less than one time per week) that does not meet proposed criteria for CB
- unstable medical illness or clinically significant abnormalities on laboratory tests or physical examination at screen
- history of seizures
- myocardial infarction within 6 months
- current pregnancy or lactation, or inadequate contraception in women of childbearing potential
- a need for medication other than memantine with possible psychotropic effects or unfavorable interactions;
- clinically significant suicidality;
- current Axis I disorder determined by the SCID and SCID-compatible modules for impulse control disorders, except for nicotine dependence
- lifetime history of bipolar disorder type I or II, dementia, schizophrenia, or any psychotic disorder determined by SCID
- current or recent (past 3 months) DSM-IV substance abuse or dependence;
- positive urine drug screen at screening
- initiation of psychotherapy or behavior therapy within 3 months prior to study baseline
- previous treatment with memantine
- treatment with investigational medication or depot neuroleptics within 3 months, with fluoxetine within 6 weeks, or with other psychotropics within 2 weeks prior to study baseline
Key Trial Info
Start Date :
December 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
August 1 2010
Estimated Enrollment :
10 Patients enrolled
Trial Details
Trial ID
NCT00830375
Start Date
December 1 2008
End Date
August 1 2010
Last Update
July 29 2019
Active Locations (2)
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1
Ambulatory Research Center
Minneapolis, Minnesota, United States, 55454
2
University of Minnesota
Minneapolis, Minnesota, United States, 55454