Status:
COMPLETED
Effects of Breastfeeding on Maternal Plasma Ghrelin and Peptide Tyrosine Tyrosine (PYY) Levels
Lead Sponsor:
Medical University of Vienna
Conditions:
Breastfeeding
Eligibility:
FEMALE
20-40 years
Brief Summary
Weight retention after pregnancy contributes to increasing rates of obesity. There is evidence that breastfeeding is accompanied from changes in fat mobilisation and fat mass, nevertheless there are n...
Detailed Description
The gut-brain axis is one of the main regulators of appetite (Cummings et Overduin). Responsible for this interaction are among others the appetite-controlling gut peptides: ghrelin and PYY. Ghrelin i...
Eligibility Criteria
Inclusion
- Inclusion Criteria:
- Group 1:
- healthy mothers (with normal BMI) fully breastfeeding their infants (aged 3 to 6 months) on demand
- past normal pregnancy
- Group 2:
- healthy mothers (with normal BMI) that do not breastfeed their infants (aged 3 to 6 months)
- past normal pregnancy
- Exclusion Criteria (for both groups):
- current endocrine and metabolic disease of the mother
- cardiocirculatory, kidney or liver disease of the mother
- infants having growth problems or any other current disease
Exclusion
Key Trial Info
Start Date :
July 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
November 1 2010
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT00831818
Start Date
July 1 2008
End Date
November 1 2010
Last Update
June 1 2011
Active Locations (1)
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1
AKH, Medical University of Vienna
Vienna, Austria, A-1090