Status:

COMPLETED

The Safety of Intravenous Lacosamide

Lead Sponsor:

Le Bonheur Children's Hospital

Conditions:

Epilepsy

Eligibility:

All Genders

4-35 years

Phase:

PHASE4

Brief Summary

To evaluate the safety of IV Lacosamide in children with partial-onset epilepsy, ages 4-35 years old, inclusive, who are either unable to take oral medication or require intravenous administration of ...

Detailed Description

Lacosamide tablets and intravenous formulations were both approved in the United States in the fall of 2008. Lacosamide is indicated for use as adjunctive therapy in the treatment of partial onset sei...

Eligibility Criteria

Inclusion

  • Patients must have a diagnosis of epilepsy and have received anti-epileptic drug therapy prior to initiation of IV Lacosamide
  • Patients must have a medical condition in which the parenteral administration of Lacosamide is desirable.
  • Patients may be male or female.
  • Patients must be 4 years of age or older, and less than age 35 years.
  • Patient or his / her legally authorized representative must sign an informed consent form prior to any study specific procedures.

Exclusion

  • Patients will be excluded from entry into the study if any of the following are true:
  • Patient has previously participated in any other intravenous Lacosamide study.
  • Patient has status epilepticus within the last 3 months.
  • Patient has a history of drug allergy to Lacosamide.
  • Patient is pregnant.
  • Patient has taken experimental drug within last 30 days.
  • Patient with significant hepatic or renal disease.

Key Trial Info

Start Date :

March 1 2010

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

November 1 2012

Estimated Enrollment :

40 Patients enrolled

Trial Details

Trial ID

NCT00832884

Start Date

March 1 2010

End Date

November 1 2012

Last Update

September 22 2020

Active Locations (1)

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1

LeBonheur Children's Medical Center

Memphis, Tennessee, United States, 38103