Status:

UNKNOWN

An Open Label Trial to Evaluate the Effects of a Novel Renal Multivitamin on Inflammation and Other Biomarkers in Endstage Renal Disease Patients

Lead Sponsor:

Nephrian

Conditions:

Hyperphosphatemia

Inflammation

Eligibility:

All Genders

18-80 years

Phase:

PHASE2

Brief Summary

The purpose of the study is to determine whether an ingestion of a new renal multivitamin supplement can have a beneficial effect on bone and mineral adn inflammation issues related to patients on dia...

Eligibility Criteria

Inclusion

  • End stage renal disease patients on dialysis for at least 90 days deemed to be at low risk by the investigator for being hospitalized or have concurrent infections
  • Serum phosphorous level \> 5 mg/dl
  • Stable phosphate binder regimen for 2 week prior to enrollment
  • Stable dose of Vitamin D for 4 weeks prior to enrollment
  • Stable calcimimetic dose for 4 week prior to enrollment

Exclusion

  • patients who are pregnant
  • patients who have pre existing thrombocytopenia defined as a platelet count of \<100 x 109/L
  • abnormal LFTs
  • baseline CRP \> 15 g/dl
  • known sensitivity to any of the active ingredients
  • patients who are currently enrolled in a clinical trial, or who have been in a clinical trial in the last six months
  • are currently taking any immunosuppressive medications

Key Trial Info

Start Date :

January 1 2009

Trial Type :

INTERVENTIONAL

Allocation :

ESTIMATED

End Date :

September 1 2009

Estimated Enrollment :

25 Patients enrolled

Trial Details

Trial ID

NCT00834301

Start Date

January 1 2009

End Date

September 1 2009

Last Update

February 3 2009

Active Locations (1)

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Simi Valley Dialysis Center

Simi Valley, California, United States, 93063