Status:
COMPLETED
Genetics of Type 2 Diabetes Among Han Chinese
Lead Sponsor:
National Human Genome Research Institute (NHGRI)
Conditions:
Diabetes
Hypertension
Eligibility:
All Genders
25+ years
Brief Summary
Objectives: * To conduct a genome-wide association study (GWAS) to identify susceptibility genetic variants for diabetes among Han Chinese. * To conduct resequencing of positional candidate gene/loci...
Detailed Description
This research protocol is designed to study the genetic basis of Type 2 Diabetes (T2D) in Han Chinese. This project taking place at Suizhou Central Hospital complements several years of similar resear...
Eligibility Criteria
Inclusion
- INCLUSION CRITERIA:
- Cases Men and women with confirmed type 2 diabetes mellitus that are either on treatment for diabetes or newly diagnose with blood sugar reading on more than one occasion exceeding or equal to 126 mg/dl. These persons must be above the age of 25 years. In this regard, all newly diagnosed participants will be required to visit the clinic on the following day to perform fasting blood glucose test to confirm previous results.
- Controls Men and women with fasting plasma glucose (FPG) less than 100 mg/dl (5.6 mmol/l). Controls must be above age 25 years and should be ethnically matched to the cases. Enrolled cases and controls have to be unrelated. Therefore, only one person may be enrolled from each family unless they are husband and wife.
- Attempts will be made to enroll an equal number of men and women. To ensure that ethnic distribution is maintained in the parent study, we are proposing to enroll only Han Chinese participants.
- EXCLUSION CRITERIA:
- People who do not meet the above criteria (e.g., younger than 24, without the blood sugar requirements, etc). No more than one non-spouse member of each family. No prisoners, pregnant women or fetuses will be included in this study.
Exclusion
Key Trial Info
Start Date :
February 3 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
February 3 2012
Estimated Enrollment :
2379 Patients enrolled
Trial Details
Trial ID
NCT00837408
Start Date
February 3 2009
End Date
February 3 2012
Last Update
September 25 2020
Active Locations (1)
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1
HuBei Suizhou Central Hospital
Suizhou, China