Status:
COMPLETED
Interactions Between Physical Activity and Cannabis Use in Adults
Lead Sponsor:
Vanderbilt University
Conditions:
Cannabis Dependence
Eligibility:
All Genders
18-35 years
Phase:
NA
Brief Summary
In this study the investigators will explore the relationship between physical activity and cannabis use. The investigators will compare regional brain activation detected by imaging technique(fRMI) b...
Detailed Description
It is unknown how the response of cannabis users might compare to those of non-users in response to similar dose of physical activity. We will therefore compare brain activation during craving to cann...
Eligibility Criteria
Inclusion
- Cases and Controls must:
- Be able to understand the study and provide written informed consent.
- Be male or female 18 -35 years of age.
- Be in generally good health
- If female of childbearing potential, have a negative serum pregnancy test on study day
- Cases must:
- Meet criteria for cannabis dependence as primary diagnosis as determined by the Substance Abuse module of SCID (Structured Clinical Interview for DSM-IV).
- Not currently seeking treatment for cannabis dependence.
- Have a positive urine drug test for cannabis on the study day
- Avoid alcohol and other recreational drug use (except cannabis and/or nicotine) for 48 h before testing.
Exclusion
- Cases and Controls must not:
- Be pregnant or lactating
- Have implanted electrical medical device (e.g. pacemaker, vagal nerve stimulator)
- Have non-secure metallic foreign bodies
- Have met criteria for another axis 1 diagnosis in the past 6 months
- Receive psychotropically active or vasoactive medications (within 6 weeks of screen day)
- Have chronic medical illness
- Have epilepsy
- Have a history of head injury that required hospitalization
- Have claustrophobia
- Have orthopedic or other problems precluding them from performing exercise protocol
- Have body mass index (BMI) less than 19 kg/m2
- Weighing more than 275 pounds (MRI table limit)
- Cases must not:
- Have current dependence, as determined by the SCID, on any psychoactive substance other than nicotine and/or cannabinoid
- Have any serious medical or psychiatric illnesses and/or clinically significant symptoms, which in the judgment of the PI or his/her designee would make them unsafe, or would make compliance with the study protocol difficult or put the study staff at undue risk
Key Trial Info
Start Date :
January 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2013
Estimated Enrollment :
30 Patients enrolled
Trial Details
Trial ID
NCT00838448
Start Date
January 1 2009
End Date
June 1 2013
Last Update
June 12 2013
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Vanderbilt University Medical Center
Nashville, Tennessee, United States, 37232