Status:
COMPLETED
Effect of Midodrine and Albumine in the Prevention of Complications in Cirrhotic Patients Awaiting Liver Transplantation
Lead Sponsor:
Hospital Clinic of Barcelona
Collaborating Sponsors:
Maternal-Infantil Vall d´Hebron Hospital
Hospital Universitari de Bellvitge
Conditions:
Renal Failure
Hyponatremia
Eligibility:
All Genders
18-70 years
Phase:
PHASE4
Brief Summary
The aim of this study is to evaluate the effect of prolonged administration of albumin and midodrine on the prevention of complications (renal failure, sepsis, hemorrhage, hepatic encephalopathy and h...
Detailed Description
End point: To evaluate the effect of long term administration of albumin and midodrine on the prevention of complications associated with cirrhosis in patients with cirrhosis awaiting for liver transp...
Eligibility Criteria
Inclusion
- Patients with cirrhosis in the waiting list for liver transplant
- Patients with ascites or diuretic treatment
- To have written inform consent
Exclusion
- Systolic blood pressure ≥150 mmHg and or diastolic blood pressure≥90 mmHg
- To have been treated with transjugular intrahepatic portosystemic shunt (TIPS) or surgical shunts
- Antibiotic treatment in the previous week before the inclusion in the study
- Respiratory or cardiac failure
- HIV positive
Key Trial Info
Start Date :
August 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
February 1 2016
Estimated Enrollment :
199 Patients enrolled
Trial Details
Trial ID
NCT00839358
Start Date
August 1 2008
End Date
February 1 2016
Last Update
August 18 2016
Active Locations (1)
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1
Hospital Clinic
Villarroel 170, Barcelona, Spain, 08870