Status:
COMPLETED
Changes in Ectopic Fat Following Surgically Induced Weight Loss
Lead Sponsor:
University of Texas Southwestern Medical Center
Collaborating Sponsors:
National Institutes of Health (NIH)
Conditions:
Obesity
Type 2 Diabetes
Eligibility:
All Genders
18+ years
Brief Summary
This study evaluates how ectopic fat (in the pancreas, heart, liver and skeletal muscle), visceral fat, and subcutaneous fat changes following surgically induced weight loss using gastric banding. The...
Detailed Description
We are looking for volunteers for this study,wich involves 7 visits over a period of 13 months, the first visit taking place about 2 weeks prior to the planned surgery. Visit 1 - baseline, before sta...
Eligibility Criteria
Inclusion
- Greater than 18 years old
- Fully understanding and willing to undergo study procedures
- Available for follow-up
- Understand and willing to sign informed consent
- Pharmacologic agents with the potential to change ectopic fat content (i.e. pioglitazone) are allowed if the patient has been on a stable dose for at least 3 months and plans to continue the same dose for the duration of the study
Exclusion
- Contraindication to MRI (i.e. metallic implants, severe claustrophobia, weight above 320lb)
- Contraindication to phlebotomy (i.e. no accessible veins, hemoglobin \<10 mg/dL)
- History of pancreatic disease other than diabetes
- Regular use of more than 2 alcoholic drinks per day
- Pregnancy
- Non-English speaking
Key Trial Info
Start Date :
August 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
December 1 2012
Estimated Enrollment :
20 Patients enrolled
Trial Details
Trial ID
NCT00840307
Start Date
August 1 2008
End Date
December 1 2012
Last Update
December 13 2017
Active Locations (1)
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1
University of Texas Southwestern
Dallas, Texas, United States, 75390