Status:
COMPLETED
Effect of Gastric Bypass-induced Weight Loss on Myocardial Structure, Function and Metabolism
Lead Sponsor:
Washington University School of Medicine
Conditions:
Obesity
Gastric Bypass
Eligibility:
All Genders
18-55 years
Brief Summary
Obesity affects more than 43 million Americans and is associated with an increased incidence of heart failure, sudden death, and cardiovascular death. We have shown that increasing obesity is independ...
Detailed Description
Thirty obese patients who weigh \<350#, the weight limit of the PET table, who are to undergo gastric bypass will be enrolled in this study. Written, informed consent approved by the Institutional Rev...
Eligibility Criteria
Inclusion
- Subjects that will undergo gastric bypass surgery will be included in the study.
Exclusion
- Subjects who have a history of insulin-requiring diabetes, ≥Class II hypertension, cardiac disease, major systemic disease, of smoking cigarettes with in the last 12 months, who are pregnant or taking vasoactive or lipid-lowering medications will be excluded because these conditions may affect our cardiac endpoints. Subjects unable to give informed consent will be excluded. Subjects \> 350# (the weight limit of the PET table) will be excluded.
Key Trial Info
Start Date :
July 1 2005
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
June 1 2014
Estimated Enrollment :
18 Patients enrolled
Trial Details
Trial ID
NCT00841009
Start Date
July 1 2005
End Date
June 1 2014
Last Update
May 4 2016
Active Locations (1)
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1
Washington University in St. Louis
St Louis, Missouri, United States, 63110