Status:
WITHDRAWN
Chronic Rhinosinusitis With or Without Nasal Polyps Steroid Study
Lead Sponsor:
Northwestern University
Collaborating Sponsors:
National Heart, Lung, and Blood Institute (NHLBI)
Conditions:
Chronic Sinusitis
Rhinosinusitis
Eligibility:
All Genders
18-70 years
Phase:
PHASE4
Brief Summary
This is a study to evaluate the cause of chronic sinus disease. Oral steroids have long been used in the treatment of inflammatory conditions including chronic sinusitis, asthma, and arthritis. Howeve...
Detailed Description
The purpose of this research study is to better understand how this potential treatment option, oral steroids, affects biochemical substances that have been associated with the development of chronic ...
Eligibility Criteria
Inclusion
- Ages 18 years to 70 years
- Diagnosis of chronic rhinosinusitis (CRS) with nasal polyps (NP) and will be undergoing sinonasal surgery for this condition
- Diagnosis of CRS without NP and will be undergoing sinonasal surgery for this condition
- No diagnosis of CRS and NP and will be undergoing nasal surgery (septoplasty/rhinoplasty, nasal fracture repair,etc.)
Exclusion
- Ages younger than 18 years and ages older than 70 years
- Diagnosis of an established immunodeficiency, pregnancy, coagulation disorder, a diagnosis of allergic fungal sinusitis (AFS), or cystic fibrosis
- Those with CRS with or without NP in whom systemic steroid therapy would be contraindicated
- Those who are dependent on systemic steroid therapy for sinonasal disease or any other condition
Key Trial Info
Start Date :
July 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 30 2019
Estimated Enrollment :
Patients enrolled
Trial Details
Trial ID
NCT00841802
Start Date
July 1 2008
End Date
June 30 2019
Last Update
April 2 2020
Active Locations (1)
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1
Northwestern University
Chicago, Illinois, United States, 60611