Status:
COMPLETED
The Role of Pulsatile Insulin Secretion (A Study Investigating the Effects of Partial Pacreatectomy on Glucose Metabolism)
Lead Sponsor:
University of California, Los Angeles
Collaborating Sponsors:
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Conditions:
Impaired Glucose Tolerance
Eligibility:
All Genders
18-80 years
Brief Summary
The purpose of this study is to examine changes in sugar metabolism that may occur in subjects who have previously had part of their pancreas removed due to a benign lesion.
Detailed Description
Beta cells of the pancreas are the insulin producing cells. People with impaired fasting glucose have a beta cell mass \~50% of that of normal glucose tolerant subjects. A 2006 canine study by Dr. Pe...
Eligibility Criteria
Inclusion
- Male and Female subjects
- 18-80 years of age who have had
- partial pancreatectomy due to a benign lesion
- OR are healthy control subjects
- are willing to fast (nothing to eat or drink for 10 hours)prior to visits
Exclusion
- Pancreatic malignancy
- Chronic pancreatitis
- Pregnant
- On steroid medications such as prednisone
Key Trial Info
Start Date :
December 1 2008
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
October 1 2009
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT00841867
Start Date
December 1 2008
End Date
October 1 2009
Last Update
November 17 2016
Active Locations (1)
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1
UCLA General Clinical Research Center (GCRC)
Los Angeles, California, United States, 90024