Status:
COMPLETED
The Aging Endocrine Pancreas: Characterization of the Entero-insular Axis Physiology in the Elderly
Lead Sponsor:
University of Campinas, Brazil
Conditions:
Diabetes Mellitus, Type 2
Insulin Resistance
Eligibility:
All Genders
35-80 years
Brief Summary
Like most endocrine axes, the entero-insular axis is expected to go through an age-related physiological deterioration, what might contribute to special features of the elderly onset type 2 diabetes i...
Eligibility Criteria
Inclusion
- Stable weight (\< 5% variation) within the last three months
- Age: 35 to 50 years old for middle-age group, and 65 to 80 years old for elderly group.
- BMI: 20 to 29.9 kg/m2
- Normal glucose tolerance (NGT) for groups Elderly and Middle-age
Exclusion
- Use of estrogen, progestogen or systemic corticosteroids.
- Hepatic cirrhosis, renal failure or any clinical condition with impaired insulin sensitivity
- Smoking
- Obesity
- Uncontrolled systemic or debilitating diseases
Key Trial Info
Start Date :
June 1 2009
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
September 1 2010
Estimated Enrollment :
24 Patients enrolled
Trial Details
Trial ID
NCT00843479
Start Date
June 1 2009
End Date
September 1 2010
Last Update
April 22 2013
Active Locations (1)
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1
LIMED (Laboratory of Investigation of Metabolism and Diabetes)/GASTROCENTRO/Univeristy of Campinas (UNICAMP)
Campinas, São Paulo, Brazil