Status:

COMPLETED

Cognitive Deficits in Major Depressive Disorder and Bipolar Disorder, Depressed Type: Prevalence and Improvement With Treatment of Depressive Symptoms

Lead Sponsor:

Massachusetts General Hospital

Conditions:

Major Depression

Bipolar Disorder

Eligibility:

All Genders

18+ years

Phase:

NA

Brief Summary

The purpose of this research study is to learn more about cognitive deficits in people with certain mood disorders. The mood disorders are Major Depressive Disorder (MDD) and Bipolar disorder, depress...

Eligibility Criteria

Inclusion

  • Eligible subjects will be inpatients admitted to the Massachusetts General Psychiatric inpatient service, Blake 11 with diagnoses of MDD with and without psychotic features and BPDD with and without psychotic features.
  • Subjects will include men and women aged 18-85.
  • Competent to give informed consent.

Exclusion

  • Patients with illnesses that impair cognitive functioning including: vascular dementia, and neurological illnesses including Parkinson's Disease, Huntington's Disease, multiple sclerosis, and Alzheimer's Disease.
  • The following DSM-IV diagnoses: schizophrenia, schizoaffective disorder, delusional disorder, organic mental disorder, substance use disorders including alcohol, active within the past 6 months, acute bereavement, and psychotic disorder not elsewhere classified.
  • Pregnant women

Key Trial Info

Start Date :

December 1 2007

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

December 1 2012

Estimated Enrollment :

33 Patients enrolled

Trial Details

Trial ID

NCT00844974

Start Date

December 1 2007

End Date

December 1 2012

Last Update

November 18 2013

Active Locations (1)

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1

Massachusetts General Hospital

Boston, Massachusetts, United States, 02114