Status:
COMPLETED
Epidemiology and Pathogenesis of HIV-Associated Pulmonary Hypertension
Lead Sponsor:
University of California, San Francisco
Conditions:
HIV Infection
Pulmonary Hypertension
Eligibility:
All Genders
18+ years
Brief Summary
The purpose of this study is to describe the epidemiology of pulmonary hypertension in individuals with HIV infection and to investigate its pathogenesis. We propose to conduct a prospective observati...
Eligibility Criteria
Inclusion
- Infection with HIV greater than 6 months in duration
- Right heart catheterization showing PASP \> 30mm Hg
- Ability to provide reliable history of HIV medications or has received the majority of medical care from San Francisco General Hospital with available records of medical treatment.
- Ability to participate in follow-up for the duration of the study.
Exclusion
- Known significant cardiovascular disease, including clinically significant valvular heart disease, congenital heart disease, current or prior symptomatic coronary disease, or known cardiomyopathy.
- Any known pulmonary disease that could potentially cause pulmonary hypertension.
- A pO2 by pulse oximetry below 90% on room air.
- Obstructive sleep apnea.
- Known collagen vascular disease.
- History of anorexigen use
- 7\. Age less than 18 years old.
- 8\. Other co-morbidities for which the investigators, in conjunction with the primary care provider, believe render the participant with an expected survival of 6 months or less.
Key Trial Info
Start Date :
November 1 2007
Trial Type :
OBSERVATIONAL
Allocation :
ACTUAL
End Date :
January 1 2021
Estimated Enrollment :
365 Patients enrolled
Trial Details
Trial ID
NCT00845013
Start Date
November 1 2007
End Date
January 1 2021
Last Update
November 10 2021
Active Locations (1)
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1
University of California, San Francisco
San Francisco, California, United States, 94110