Status:
COMPLETED
PET Imaging Study on Occupancy of Dopamine D2 Receptors and Genotypes After Bupropion Administration
Lead Sponsor:
Seoul National University Hospital
Collaborating Sponsors:
Ministry of Health, Welfare and Family Affairs
Korea National Enterprise for Clinical Trials
Conditions:
Smoking
Eligibility:
MALE
20-50 years
Phase:
PHASE4
Brief Summary
Bupropion has different effects on D2 dopamine receptors according to genotype.
Detailed Description
Open, one arm, single sequence, 2-period, study stratified into 2 DRD2 genotype groups For subjects who volunteer to cease smoking, genotypes are investigated. Twelve subjects are enrolled (6 - DRD2 T...
Eligibility Criteria
Inclusion
- Active smoker (more than 10 cigarettes per day for the past 2 years)
Exclusion
- Medical or psychiatric co-morbidity
- Hypersensitive to bupropion
Key Trial Info
Start Date :
November 1 2008
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
June 1 2009
Estimated Enrollment :
12 Patients enrolled
Trial Details
Trial ID
NCT00846339
Start Date
November 1 2008
End Date
June 1 2009
Last Update
February 23 2011
Active Locations (1)
Enter a location and click search to find clinical trials sorted by distance.
1
Seoul National University Hospital
Seoul, South Korea, 110-744