Status:
UNKNOWN
Markers of Oxidative Stress Diastolic Dysfunction
Lead Sponsor:
Emory University
Conditions:
Diastolic Heart Failure
Diastolic Dysfunction
Eligibility:
All Genders
18-65 years
Brief Summary
This study is to look at the differences between people who have evidence of abnormal heart relaxation (diastolic dysfunction) on sound wave pictures of the heart (an echocardiogram) compared to those...
Detailed Description
Background Introduction: The incidence of congestive heart failure (CHF) has been increasing significantly. Between 1971 and 1994, the crude hospitalization rate for heart failure increased from 8.2...
Eligibility Criteria
Inclusion
- Patients age ≥ 18 years.
- Able to provide informed consent.
- Cases must have diastolic dysfunction documented by echocardiography an interval of six month before the time of enrollment.
Exclusion
- Control subjects must not have diastolic dysfunction documented by echocardiography in an interval of six month before the time of enrollment.
- All subjects will be in sinus rhythm.
- All patients will have a left ventricular ejection fraction of \> 55% but less than \< 70%.
- All patients will have normal systolic and diastolic cardiac dimensions on the qualifying echocardiogram.
Key Trial Info
Start Date :
July 1 2006
Trial Type :
OBSERVATIONAL
Allocation :
ESTIMATED
End Date :
July 1 2010
Estimated Enrollment :
50 Patients enrolled
Trial Details
Trial ID
NCT00846404
Start Date
July 1 2006
End Date
July 1 2010
Last Update
February 18 2009
Active Locations (1)
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1
Atlanta VAMC
Decatur, Georgia, United States, 30033