Status:

COMPLETED

Treatment With Sitagliptin for Reactive Hypoglycemia Secondary to Dysinsulinism

Lead Sponsor:

Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

Collaborating Sponsors:

Merck Sharp & Dohme LLC

Conditions:

Reactive Hypoglycemia

Eligibility:

All Genders

18-45 years

Phase:

PHASE4

Brief Summary

The purpose of this study is to determine whether sitagliptin is effective in the treatment of reactive hypoglycemia by dysinsulinism.

Detailed Description

Symptomatic reactive hypoglycemia is an abnormal glucose decrease after meal ingestion. Patients with this abnormality as an early manifestation of glucose intolerance are at higher risk of type 2 dia...

Eligibility Criteria

Inclusion

  • Clinical and biochemical diagnosis of prediabetic reactive hypoglycemia
  • Must be able to swallow tablet
  • Negative pregnancy test (when appropriate)

Exclusion

  • Renal insufficiency
  • Hepatic insufficiency
  • Diabetes (any type)

Key Trial Info

Start Date :

December 1 2008

Trial Type :

INTERVENTIONAL

Allocation :

ACTUAL

End Date :

March 1 2011

Estimated Enrollment :

20 Patients enrolled

Trial Details

Trial ID

NCT00847080

Start Date

December 1 2008

End Date

March 1 2011

Last Update

April 26 2011

Active Locations (1)

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1

Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

Mexico City, Mexico City, Mexico, 14000