Status:
COMPLETED
Comparative Study of Two Brands of Heparin Already on the Market
Lead Sponsor:
Southlake Regional Health Centre
Conditions:
Coronary Artery Bypass Grafting
Eligibility:
All Genders
18-90 years
Phase:
NA
Brief Summary
Two heparin brands have been in the market in Canada for several years. Heparin Leo from Leo Pharma and Hepalean from Organon. The former is standardized by B.P (British pharmacopeia) while the latter...
Detailed Description
The study protocol attempts not to change the normal protocol for cardiac surgery too much. The two different brands of heparin-Heparin Leo (Leo pharma) and Hepalean (Organon) are randomized by the f...
Eligibility Criteria
Inclusion
- Isolated Coronary Artery Bypass Surgery
- Normal Hematocrit
- Normal Creatinine
- Normal Liver function
Exclusion
- Re-do
- Combination procedure
- Valve repair/replacement
- IABP-pre/Intra/Post-op
- Cell saver intra-op
- Anemia (70 g/L)/Bleeding disorder, e.g.,: Jehovah's witness, hemophilia etc.
- Use of aprotinin
- Small adult \< 50 kg
- Aortic surgery with/without circ. arrest
- Emergent patient with heart failure
Key Trial Info
Start Date :
September 1 2006
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
December 1 2007
Estimated Enrollment :
100 Patients enrolled
Trial Details
Trial ID
NCT00848796
Start Date
September 1 2006
End Date
December 1 2007
Last Update
February 20 2009
Active Locations (1)
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1
Southlake Regional Health Centre
Newmarket, Ontario, Canada, L3Y 2P9