Status:
TERMINATED
Comparing the Effects of Two Beta Blockers,Metoprolol and Nebivolol,on Ambulatory Blood Pressure and Basal Metabolic Rate
Lead Sponsor:
University of Mississippi Medical Center
Conditions:
Hypertension
Eligibility:
All Genders
18+ years
Phase:
NA
Brief Summary
The purpose of the study is to compare the effects of nebivolol and metoprolol on 24-hour ambulatory blood pressure characteristics and basal metabolic rates in patients with hypertension.
Eligibility Criteria
Inclusion
- 18 years old or older
- currently be treated at a University of MS Medical Center Internal Medicine Clinics
- currently taking metoprolol succinate for hypertension
- have their hypertension controlled (\<140/90).
Exclusion
- uncontrolled hypertension
- severe renal or moderate hepatic impairment
- currently taking CYP 2D6 inducers/inhibitors
- recent stroke (less than 6 months)
- recent myocardial infarction (less than 6 months)
- congestive heart failure
- diagnosed obstructive sleep apnea
- atrial fibrillation
- arm circumference \>50 cm
Key Trial Info
Start Date :
January 1 2009
Trial Type :
INTERVENTIONAL
Allocation :
ACTUAL
End Date :
November 1 2010
Estimated Enrollment :
1 Patients enrolled
Trial Details
Trial ID
NCT00849810
Start Date
January 1 2009
End Date
November 1 2010
Last Update
March 19 2013
Active Locations (1)
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1
University of Mississippi Medical Center
Jackson, Mississippi, United States, 39216