Status:

COMPLETED

Vascular Access for Hemodialysis and Inflammation

Lead Sponsor:

IRCCS Azienda Ospedaliero-Universitaria di Bologna

Conditions:

Vascular Access for Hemodialysis and Inflammation

Eligibility:

All Genders

18-85 years

Brief Summary

The aim of the present study was to investigate patients free of active infection and/or thrombosis to assess if the type of vascular access (AVF, AVG, TCC), could influence: 1. the levels of serolog...

Detailed Description

Patients with AVF assumed ticlopidine 250 mg/die, patients with TCC and AVG assumed warfarin to maintain target INR between 1.8 and 2.5. Six wash out consecutive sessions were carried out before star...

Eligibility Criteria

Inclusion

  • All the patients recruited for the study were infection and thrombosis free from almost 6 months.
  • No patients included had autoimmune disease, hepatic failure, diabetes or malignancy.
  • Patients were not administered ACE inhibitors, angiotensin receptor antagonists, antiinflammatory or immunosuppressive drugs.
  • All the patients had residual GFR \< 5 ml/min.
  • The vascular access considered were placed from at least 6 months.

Exclusion

  • Patients with recirculating vascular access \> 10% were excluded from the study.
  • Patients with acute cardiovascular accident in the last 15 days before starting the study.

Key Trial Info

Start Date :

January 1 2000

Trial Type :

OBSERVATIONAL

Allocation :

ACTUAL

End Date :

December 1 2008

Estimated Enrollment :

458 Patients enrolled

Trial Details

Trial ID

NCT00850707

Start Date

January 1 2000

End Date

December 1 2008

Last Update

March 18 2021

Active Locations (1)

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Page 1 of 1 (1 locations)

1

Nephrology Dialysis Transplantation Unit St.Orsola University Hospital

Bologna, Italy, 40138